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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
RB1CC1
All Species:
10
Human Site:
S1221
Identified Species:
22
UniProt:
Q8TDY2
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8TDY2
NP_001077086.1
1594
183091
S1221
K
D
R
Q
K
L
V
S
S
Q
E
Q
D
R
E
Chimpanzee
Pan troglodytes
XP_001149458
1594
182953
S1221
K
D
K
Q
K
L
V
S
S
Q
E
Q
D
R
E
Rhesus Macaque
Macaca mulatta
XP_001102620
1594
183007
I1221
K
D
K
Q
K
L
V
I
S
Q
E
Q
D
R
E
Dog
Lupus familis
XP_535068
1593
183137
M1220
K
D
R
E
K
F
V
M
S
K
E
Q
D
R
E
Cat
Felis silvestris
Mouse
Mus musculus
Q9ESK9
1588
182346
K1217
K
D
K
E
R
L
V
K
N
H
E
Q
D
K
E
Rat
Rattus norvegicus
NP_001101371
1588
182209
M1217
K
D
K
Q
R
L
A
M
N
H
E
Q
D
K
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001515279
1595
182705
L1225
E
D
K
E
K
I
L
L
K
Q
E
Q
D
R
E
Chicken
Gallus gallus
XP_001232350
1598
182600
S1228
E
E
K
D
L
L
V
S
N
Q
E
Q
D
K
Q
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_996156
1357
152264
P1043
V
V
D
I
N
Q
I
P
L
P
Y
Y
A
I
G
Honey Bee
Apis mellifera
XP_391908
1303
147219
M990
I
E
E
K
D
R
E
M
E
M
F
R
R
R
E
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P61430
856
99003
S543
Q
Y
D
L
M
L
E
S
K
Q
L
E
L
S
R
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
98.4
95.3
N.A.
89
89.4
N.A.
81
79.7
N.A.
N.A.
N.A.
22.9
23.5
N.A.
N.A.
Protein Similarity:
100
99.7
99.2
97.7
N.A.
94.1
94.4
N.A.
89.7
89.4
N.A.
N.A.
N.A.
42.8
41.2
N.A.
N.A.
P-Site Identity:
100
93.3
86.6
73.3
N.A.
53.3
53.3
N.A.
53.3
46.6
N.A.
N.A.
N.A.
0
13.3
N.A.
N.A.
P-Site Similarity:
100
100
93.3
86.6
N.A.
86.6
80
N.A.
86.6
86.6
N.A.
N.A.
N.A.
6.6
33.3
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
21.5
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
35.7
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
20
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
33.3
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
10
0
0
0
0
0
10
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
64
19
10
10
0
0
0
0
0
0
0
73
0
0
% D
% Glu:
19
19
10
28
0
0
19
0
10
0
73
10
0
0
73
% E
% Phe:
0
0
0
0
0
10
0
0
0
0
10
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% G
% His:
0
0
0
0
0
0
0
0
0
19
0
0
0
0
0
% H
% Ile:
10
0
0
10
0
10
10
10
0
0
0
0
0
10
0
% I
% Lys:
55
0
55
10
46
0
0
10
19
10
0
0
0
28
0
% K
% Leu:
0
0
0
10
10
64
10
10
10
0
10
0
10
0
0
% L
% Met:
0
0
0
0
10
0
0
28
0
10
0
0
0
0
0
% M
% Asn:
0
0
0
0
10
0
0
0
28
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
10
0
10
0
0
0
0
0
% P
% Gln:
10
0
0
37
0
10
0
0
0
55
0
73
0
0
10
% Q
% Arg:
0
0
19
0
19
10
0
0
0
0
0
10
10
55
10
% R
% Ser:
0
0
0
0
0
0
0
37
37
0
0
0
0
10
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
10
10
0
0
0
0
55
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
10
0
0
0
0
0
0
0
0
10
10
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _